Deciphering dengue fever transmission on higher-order networks.
Linhe Zhu +2
Dengue fever is a viral infection transmitted to humans through the bites of infected mosquitoes.
PubMed→Monolith 02
AI diagnostic tools for diseases that kill disproportionately in South Asia. The diseases that Western AI labs do not build for.
Phase 01 active. First published research output: December 2026.
Data-partnership discussions active with three Sri Lankan hospital networks.
First published research output: December 2026.
Ethics & data integrity
All medical research is conducted under international ethical standards (COPE, ICMJE, the Helsinki Declaration). Research involving patient data requires IRB/ethics-board approval before access. IRB application status: submitted, pending. Current stage: publicly available datasets only (PubMed, ClinicalTrials.gov). No patient data is processed until approval is received and documented.
Live from the frontier
Questions
The Advanced Medicine laboratory researches AI diagnostic tools for diseases disproportionately affecting South Asia: dengue, malaria, typhoid, and thalassemia. Dengue alone causes an estimated 390 million infections annually (WHO), 96% of them in tropical and subtropical regions including Sri Lanka.
The first published research output is targeted for December 2026: a computational analysis of binding-site predictions for dengue NS5 polymerase, using AlphaFold-generated structures cross-referenced with existing approved-compound databases for repurposing candidates.
No patient data is processed until IRB/ethics-board approval is received and documented. All current medical research uses publicly available datasets only — PubMed and ClinicalTrials.gov. Data-partnership discussions are active with Sri Lankan hospital networks.
Medical research follows COPE guidelines, ICMJE recommendations, and the Helsinki Declaration. Research involving patient data requires IRB approval before access, de-identification before any data enters ASI systems, and a published ethics statement with every output.
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Linhe Zhu +2
Dengue fever is a viral infection transmitted to humans through the bites of infected mosquitoes.
PubMed→Le Thanh Trang +7
Dengue fever (DF) remains one of the most significant mosquito-borne diseases in tropical and subtropical regions, particularly in Ho Chi Minh City (HCMC), Vietnam.
PubMed→Carlos Espinal +18
Dengue remains the most important arboviral disease in the Americas and a growing global public health threat.
PubMed→Danyang Li +3
Dengue fever poses a major global health threat, with Brazil experiencing severe recurrent outbreaks driven by climatic, socio-economic and mobility factors.
PubMed→Md Muqtadir Fuad +2
Dengue remains a major public health problem in endemic regions, including Bangladesh.
PubMed→Darllan Collins da Cunha E Silva +6
Dengue is an arboviral disease of high public health relevance, characterized by pronounced temporal variability, nonlinearity, and recurrent outbreaks, which pose challenges to epidemiological surveillance and decision-making.
PubMed→